Scaling ActiveMQ broker for higher load (Network of brokers)

Hi,

I am currently using ActiveMQ 5.10 and running one message broker. In my
setup clients are continuously increasing by which load on the message
broker is getting higher.

I want to scale my ActiveMQ broker setup to handle such kind of load. After
reading some documentation, I think Network of broker is the best option to
decrease load from one broker and spread it between network of brokers.

Is there a way by which I can use one broker for some particular
destinations and another for some other destinations (may be topics and
queues are on different broker) ? Or Can I have one broker for persistent
message and another for non-persistent messages ?

How many brokers should I use and what are all configuration option for the
network (like clients connection to the broker are separated by persistent
or destination or connection etc)?

Thanks,
Anuj